Anti-DSC1 Polyclonal Antibody

商品货号：	商品品牌：	规格	基本售价：	选择规格
K001829P-50ul	solarbio	50ul	960.00元
K001829P-100ul	solarbio	100ul	1600.00元

英文名称	Anti-DSC1 Polyclonal Antibody
别名	CDHF1;DG2/DG3
应用	WB IHC
稀释比例	WB 1:500-2000. IHC 1:50-200.
交叉反应	Human Mouse Rat
蛋白分子量	100kDa
Gene ID	1823
保存	Store at -20°C. Avoid freeze / thaw cycles.
储存液	Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
纯化方法	Affinity purification
亚型	IgG
免疫原	Recombinant protein of human DSC1
性状	液体
Public Immunogen Range	Recombinant protein of human DSC1
Subcellular Locations	Cell junction Cell membrane Single-pass type I membrane protein desmosome
Swiss Prot	Q08554
克隆类型	Polyclonal Antibody
背景资料	The protein encoded by this gene is a calcium-dependent glycoprotein that is a member of the desmocollin subfamily of the cadherin superfamily. These desmosomal family members, along with the desmogleins, are found primarily in epithelial cells where they constitute the adhesive proteins of the desmosome cell-cell junction and are required for cell adhesion and desmosome formation. A subtype of IgA pemphigus, a life-threatening autoimmune disease, is characterized by the presence of autoantibodies that target the encoded protein. The desmosomal family members are arranged in two clusters on chromosome 18. Alternative splicing of this gene results in multiple transcript variants. At least one of these variants encodes a preproprotein that is proteolytically processed to generate the mature protein.